The answer so far
A medicine’s expiry date is based on stability when it is stored as labelled. It does not guarantee quality after unassessed heat, moisture or freezing. Food and supplement dates can follow different systems, and some products also have a separate limit after opening.123
On this page
Does the expiry date tell you whether a product is still usable? Choose a step to explore this subject in more detail.
The date is attached to storage conditions
The FDA explains that medicine expiry dates are based on stability under the labelled conditions. The date does not mean a medicine becomes unsafe at an exact instant. It also does not prove the medicine remains effective after expiry or poor storage. Follow the label and ask a pharmacist about replacement or continuing treatment if needed.12
Opening and changing containers
Some products have a separate limit after opening, preparation or first use. Moving a medicine to a pill organiser or another bottle can change its protection from light or moisture and separate it from its identifying label. The effect depends on the product. Keep the original instructions and ask a pharmacist about your medicine.
For example, the January 2026 US FDA label says to keep Rybelsus and Ozempic tablets in their original closed bottle until use, not another container. This applies to those US tablets, not every semaglutide product; see the product-specific guide. Follow the label for any desiccant rather than assuming it is safe to remove or ingest.324
What sight and smell can—and cannot—tell you
A changed appearance, broken seal, unusual smell or signs of contamination are reasons to check the product and label. But a product that looks unchanged is not necessarily still potent, pure or sterile. Do not taste a product to test it.1
Medicines are not the same as food dates
A food’s best-before or use-by date and a supplement label are not automatically equivalent to a medicine expiry date. Terms also differ by country. Read the exact label and consult the appropriate local authority; this guide cannot give a universal extension.
See protein powder and drink storage, probiotic storage and expiry, and vitamin A forms and amounts.1
Further reading
Trusted external resources selected to help explain this page. They open in a new tab.
- Expiration Dates: Questions and Answers ↗Addresses drug expiration dates and labelled storage conditions; not a stability study of a particular supplement.
- Don’t Be Tempted to Use Expired Medicines ↗General medicine storage guidance; individual product labels can differ.
- Expiration Dating and Stability Testing for Human Drug Products ↗FDA technical guide dated 18 October 1985 on formulation, containers and storage; not a product-specific expiry extension or proof of current regulatory requirements.
Sources, kept close.
Selected supporting sources; this is not a complete literature review.
- Expiration Dates: Questions and AnswersU.S. Food and Drug Administration · Regulator guidance for human medicines
- Don’t Be Tempted to Use Expired MedicinesU.S. Food and Drug Administration · Regulator consumer guidance
- Expiration Dating and Stability Testing for Human Drug ProductsU.S. Food and Drug Administration · Regulator inspection guidance
- Rybelsus and Ozempic tablets: US prescribing information, January 2026U.S. Food and Drug Administration · FDA-approved prescribing information
